Purpose The blood supply of meniscus is an essential indicator for the prognosis of meniscal problems. Intravoxel incoherent motion (IVIM) model were used to estimate the change of vasculature in normal, degenerated and teared meniscus. Method 50 patients with knee problems were recruited and the posterior horns of the medial menisci (PMM) were counted in. The menisci were further divided in normal, degenerated and teared groups according to the five-step scoring scheme by PDWI. For each subject, diffusion-weighted image with multiple b values were acquired. The perfusion fraction f, pseudodiffusion coefficient D* and diffusion coefficient D were calculated. The values of f, D* and D in the red zone of PMM among the normal, degenerated and teared meniscus groups were analyzed by one-way ANOVA. Further pairwise comparisons were performed. Results Among the 50 PMMs, 35 normal menisci, 8 degenerative changes and 7 meniscal tears were confirmed by PDWI. In comparison of f among the 3 groups of PMM showed a significant difference (P = 0.043) by one-way ANOVA. In further pairwise comparison, a significant reduction of f value (P = 0.013) was observed in red zone of teared meniscus compared with the normal subjects. No significant differences were derived between normal and degenerative groups and between degenerative and teared groups. The D* and D values didnt show significant difference of PMM among the 3 groups. Conclusion The IVIM profusion fraction f could detect the microvascular supply of the meniscus and may be a potential predictor for prognosis of meniscal tears.