Purpose: Morindacitrifolia(Noni),an important traditional medicinal plant used in patients with bone fractures or dislocation to promote connective tissue repair and to reduce inflammation.However,the influence of Morindacitrifolia on osteogenic differentiation is yet to be clarified.The objective of this study is to evaluate the effect of Noni juice(NJ)on the proliferation rate of bone marrow mesenchymal stem cells(MSC),the differentiation of marrow mesenchymal stem cells into osteoblasts(osteoblastogenesis)and the level of mineralization.