表观遗传因子CDYL负性调控海马神经元树突分枝

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户:spendtime
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  目的:神经元树突分枝是神经环路形成的决定因素之一。探讨树突形态发生的分子机制对于理解神经环路的建立具有重要意义。神经元树突分枝的复杂程度受到胞外因素,细胞质组分和细胞核过程的协同调控,最近的研究表明细胞核内的生物学过程,尤其是表观遗传在树突分枝的复杂程度上起着越来越重要的作用,而组蛋白的甲基化作为表观遗传修饰的一种重要方式,其是否也参与调控神经元树突分枝还不清楚。
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