【摘 要】
：
Estrogen plays an important role in follicular growth, selection and ovulation.The aim of the study is to investigate the function of estrogen in mouse follicul
【机 构】
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InstituteofReproduction&Development,FudanUniversity,Shanghai200011ShanghaiInstituteofPlannedParentho
【出 处】
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中国动物学会细胞与分子显微技术学分会第十七次学术研讨会
论文部分内容阅读
Estrogen plays an important role in follicular growth, selection and ovulation.The aim of the study is to investigate the function of estrogen in mouse follicular development and its involved mechanism.In our study, female C57BL/6 mice aged 3 weeks were injected intraperitoneally with 10μg/gBW estradiol benzoate or diethylstilbestrol for 5 days.We found that estrogen or estrogen analogues can promote follicle synchronized development in prepubertal mouse like PCOS.To detect the oocyte quality, the injected young mice were superovulated and oocytes fertilized in vitro, results show there is no difference in the number of harvested eggs, in vitro fertilization rate, 2-cell embryo rate and blastocyst rate compared to control.
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