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  5. THE EFFECT OF CLOSING OF MITOCHONDRIAL PERMEABILITY TRANSITION PORE ON IMMATURE RABBIT HEART PROTECT

THE EFFECT OF CLOSING OF MITOCHONDRIAL PERMEABILITY TRANSITION PORE ON IMMATURE RABBIT HEART PROTECT

来源 :第七届亚洲体外循环学术会议暨第三届全国体外循环学术会议 | 被引量 : 0次 | 上传用户：huangys
【摘 要】
：
Objective:To observe the cardioprotective effect of hyperkalemic cardioplegic solution enriched with either mitochondrial permeability transition pore inhibitor or potassium channel openers on rabbit
【作 者】
：
LIN Ru FAN Yong 
【机 构】
：
Affiliated Children's Hospital,School of Medicine,Zhejiang University,China
【出 处】
：
第七届亚洲体外循环学术会议暨第三届全国体外循环学术会议
【发表日期】
：
2007年12期
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　　Objective:To observe the cardioprotective effect of hyperkalemic cardioplegic solution enriched with either mitochondrial permeability transition pore inhibitor or potassium channel openers on rabbit immature heart subjected ischemia.Methods:Forty-five immature rabbit hearts were randomly divided into 5 groups.After control perfusion in modified Langendorff mode with Krebs-Henseleit bicarbonate buffer for 20 minutes,the isolated immature rabbit hearts were infused with 20ml different cardioplegia.
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