Objective: Cyclooxygenase (COX) 1 is a key enzyme in the biosynthesis of prostaglandins (PGs) from arachidonic acid (AA).Unlike COX2, which is induced by in
Background: Tumor associated macrophages (TAMs) and their alternative activation contribute greatly to the development of hepatocellular carcinoma (HCC).
Tim-3 is well known to interact with its natural ligand, Galectin9, to dampen Th1 immunity and promote peripheral tolerance.However, the function of Galecti