Lack of association of the MTHFR A1298C polymorphism with susceptibility to malignant lymphoma a sys

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户:hailongsky
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Malignant lymphomas are a very heterogeneous group of tumours and the etiology of this disease remains unclear.Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme in folate metabolism and DNA synthesis.MTHFR A1298C polymorphism leads to reduced MTHFR activity,which may lead to cancer development.However,the association between MTHFR A1298C polymorphism and lymphoma risk is uncertain and controversial.
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