Allergic Bronchopulmonary Aspergillosis Presenting as tumor-like consolidation in progression

来源 :2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户:lene817
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  目的 Allergic bronchopulmonary aspergillosis (ABPA ) is a hypersensitive disease showing various radiographic and clinical manifestation. Its clinical course has not been fully understood. 方法 We herein described a case of a 35-year-old immunocompetent asthmatic woman with a huge mass on the right apex of lung. 结果 The patient came by our hospital because of persistent cough and hemoptysis. Laboratory examination showed hypereosinophilia with increased total IgE as well as Galactomannan (GM) test positive both in peripheral blood and broncho-alveolar lavage Fluid (BALF). Radiologic features in series showed a dense consolidation in progression. Histological tissues obtained under bronchoscopy were confirmed as allergic inflammation with neutrophilic and eosinophilic infiltration. On the diagnosis of ABPA, the patient was treated with systemic steroid and voriconazole (stopped ten days after the initiation due to poor tolerance). The patient visits respiratory clinic every 30 days with a stable decrease in eosinophilia and total IgE. The controlled chest CT scan showed a complete disappearance of mass with a dilated lung tissue instead.
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