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5. A genome-wide association study identifies novel genetic loci that modify pharmacokinetic-pharmacody

A genome-wide association study identifies novel genetic loci that modify pharmacokinetic-pharmacody

来源 :中国药理学会第十四次全国学术大会暨施维雅优秀青年药理学工作者奖20周年学术论坛 | 被引量 : 0次 | 上传用户：loveyue0414

【摘 要】

：

OBJECTIVE Genetic variants in the pharmacokinetic (PK) mechanism are the main underlying factors that modify the antiplatelet efficacy of clopidogrel.

【作 者】

：

ZHONG Wan-ping WU Hong CHEN Ji-yan Li Xin-xin LIN Hao-ming ZHANG Bin ZHANG Zhi-wei MA Dun-liang SUN Shuo LI Han-ping MAI Li-ping HE Gou-dong WANG Xi-pei LEI He-ping TANG Lan LIU Shu-wen ZHONG Shi-long 

【机 构】

：

Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular I

【出 处】

：

中国药理学会第十四次全国学术大会暨施维雅优秀青年药理学工作者奖20周年学术论坛

【发表日期】

：

2016年11期

【关键词】

：

clopidogrel pharmacokinetics pharmacodynamics genome-wide association study N6AM 

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　　OBJECTIVE Genetic variants in the pharmacokinetic (PK) mechanism are the main underlying factors that modify the antiplatelet efficacy of clopidogrel.

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