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5. Synthesis and DNA-cleaving activities of berberine-based metal complexes

Synthesis and DNA-cleaving activities of berberine-based metal complexes

来源 :第八届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：fuyueliang

【摘 要】

：

During the past decades, considerable interest has been attracted in transition metal complexes that are capable of binding and cleaving DNA under physiological

【作 者】

：

Wen-Hua Chen Jin-Xiang Chen Yong-Min Wang Chun-Qiong Zhou 

【机 构】

：

SchoolofPharmaceuticalSciences,SouthernMedicalUniversity,Guangzhou510515,P.R.China

【出 处】

：

第八届全国化学生物学学术会议

【发表日期】

：

2013年9期

【关键词】

：

Metal complex berberine synthesis DNA cleavage 

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论文部分内容阅读

During the past decades, considerable interest has been attracted in transition metal complexes that are capable of binding and cleaving DNA under physiological conditions.1, 2 Among them, the complexes that are based on natural products would lead to biocompatible potential (pro-)drugs with significantly enhanced bioactivities.

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