The membrane-bound mucin MUC1 glycoprotein is an attractive target for tumor immunotherapy.The tandem repeat sequence of MUC1: HGVTSAPDTRPAPGSTAPPA,has been used for vaccine development in a number of studies.[1-5] Herein,we have synthesized a series of fully synthetic glycopeptide vaccines containing the MUC1 repeat sequence.The P30 peptide FNNFTVSFWLRVPKVSASHLE was used as a T cell epitope for the activation of the T cells.