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5. Vitamin B12(VB12)-conjugated sericin micelles for targeting gastric cancer and reversing drug resist

Vitamin B12(VB12)-conjugated sericin micelles for targeting gastric cancer and reversing drug resist

来源 :第十三届全国胃癌学术会议 | 被引量 : 0次 | 上传用户：lijincai0122

【摘 要】

：

Objective To explore the synthesis procedures of Vitamin B12-modified sericinencapsulated PTX micelles,we refer to these micelles as “VB12-sericin-PBLG-PTX”,and explored the(CD320-receptor-mediated)ce

【作 者】

：

Weihong Guo Yanfeng Hu 

【机 构】

：

Nanfang Hospital,Southern Medical University,Guangdong Provincial Engineering Technology Research Ce

【出 处】

：

第十三届全国胃癌学术会议

【发表日期】

：

2018年3期

【关键词】

：

Vitamin B12 sericin gastric cancer micelle drug resistance tumour targeting 

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　　Objective To explore the synthesis procedures of Vitamin B12-modified sericinencapsulated PTX micelles,we refer to these micelles as “VB12-sericin-PBLG-PTX”,and explored the(CD320-receptor-mediated)cellular-uptake pathway of VB12-sericin-PBLG-PTX micelles,their anti-tumour properties in gastric cancer.

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