2. 您的位置
3. 首页
4. 会议论文
5. Altered expression of miR-21 is related to PTEN expression and clinicopathologic features of colorec

Altered expression of miR-21 is related to PTEN expression and clinicopathologic features of colorec

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：beichensi

【摘 要】

：

Aim: To investigate the expressions of microRNA-21 (miR-21) and PTEN in colorectal carcinoma (CRC), and explore their correlation.Methods: Real-time PCR was used to detect the expression of miR-21 in

【作 者】

：

Yi-ying WU Yuan-yuan ZHANG Shi-kun MIAO Li-ming ZHOU 

【机 构】

：

Department of Pharmacology,West China School of Preclinical and Forensic Medicine,Sichuan University

【出 处】

：

The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

：

2013年4期

【关键词】

：

colorectal carcinoma microRNA-21 (miR-21) PTEN 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Aim: To investigate the expressions of microRNA-21 (miR-21) and PTEN in colorectal carcinoma (CRC), and explore their correlation.Methods: Real-time PCR was used to detect the expression of miR-21 in 105 cases of colorectal carcinoma and tumor-adjacent normal tissue after operation.

其他文献

Association study between aberrant DNA methylation in promoter of DDAH2 gene and dysfunction of EPCs

Aim: it has been demonstrated that circulating EPCs may be a biomarker for vascular function and cardiovascular risk in patients with coronary artery disease patients (CAD).Recent studies suggest that

会议

endothelial progenitor cellsatheroslcerosisDNA methylationdimethylarginine di

Drug-drug interactions between triazoles antifungal agents and calcineurin inhibitors in hepatic tra

Aim: To assess the frequency of potential drug-drug interactions (PDDIs) and consequences of interactions between triazoles antifungal agents and calcineurin inhibitors (CNIs) in hepatic transplantati

会议

drug-drug interactionstriazoles antifungal agentscalcineurin inhibitors

An integrated approach for revaluating the rationality and safety of traditional Chinese medicine in

Aim: Authoritative evaluation criteria for the rationality and safety of traditional Chinese medicine injections (TCMIs) in clinical use have still not been established.This approach attempts to impro

会议

traditional Chinese medicine injectionsrationalitysafetydrug utilization rese

Clinical prediction and diagnosis of Alzheimer's disease based on microRNA panel

Aim: Alzheimers disease diagnosis is time-consuming and challenging, serumbased biomarkers are the least expensive and invasive modality for screening and routine monitoring.In this study, we investig

会议

Alzheimer's diseasediagnosismicroRNAbiomarkers

UCP-1 and UCP-2 gene polymorphism on patients with shivering after cesarean section under spinal ane

Aim: To study UCP-1 and UCP-2 gene polymorphism of patients shivering after cesarean section under spinal anesthesia and to explore the factors for post cesarean section shivering.Methods: 200 cases o

会议

cesarean sectionshiveringUCP-1UCP-2

Bioequivalence study of simvastatin in healthy volunteers

Aim: To assess the bioequivalence of two simvastatin tablet formulations in 24 male healthy volunteers.Methods: The study was performed according to an open-label,randomized, single-dose, two-period c

会议

simvastatinbioeuqivalenceliquid chromatography coupled to tandem mass spectrom

Determination of SHV-typed extended-spectrum β-lactamases in E.coli, K.pneumonia and P.aeruginosa of

Bacteria producing Extended-spectrum β-1actamases (ESBLs), have risen dramatically and been recognized a global healthy problem.In this research,we investigated the genotype distributed of extended-sp

会议

microbial sensitivity testsmolecular epidemiologybeta-lactamasesgenetics

One case report of intervention in immunosuppressive agents convertion from cyclosporine to tacrolim

Aim: To explore the work pattern of clinical pharmaceutical care associated with immunosuppressive agents convertion from cyclosporine to tacrolimus in renal transplant patients by the methods of ther

会议

clinical pharmacistcyclosporinetacrolimusrenal transplantationCYP3A5*3/*3 ge

Three protective CYP2E1-SNPs associated with CsA-induced liver injury in Chinese population

Aim: The purpose of this study was to evaluate the association of CYP2E1 polymorphism with CsA-induced liver injury and to elucidate the possible molecular mechanism using gene function research.Metho

会议

CYP2E1genetic polymorphismcyclosporin Adrug-induced liver injury

Identification of PEAR1 single-nucleotide polymorphisms and their influences on the variation in Pra

Aim: The platelet responses to antiplatelet drugs are highly variable.However,the associated mechanisms are poorly defined.The present study aimed to investigate PEAR1 genetic polymorphisms and pharma

会议

PEAR1Han Chinese subjectsprasugrelgenetic polymorphismpharmacodynamics