This study was conducted to investigate the effects of dietary supplementation with supercritical CO2 Ligustrum Lucidum extract (LLE) on immune responses in swine.A total of 96 healthy Duroc × Landrace × Yorkshire pigs,with an average body weight (BW) of 7.43 kg,were randomly assigned on the basis of litter,BW and sex to one of 4 dietary treatments,with 4 pens per treatment and 6 weaned piglets per pen,and were fed corn and soybean meal-based diets containing 0,0.05％,0.1％ or 0.2％ LLE.