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Fatty acid synthase(FASN)is a cytosolic enzyme to converse dietary carbohydrates to fatty acids.FASN is not expressed in some normal tissues.But it is upregulated in several human carcinomas [1].FASN was an attractive antitumor target for cancer drug discovery [2].Catechins are natural polyphenols included in tea.Some compounds with inhibition effects of FASN were found to have anti-cancer effects [3].