【摘 要】
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Background: Liver ischemia/reperfusion (I/R) injury induces the occurence of endoplasmic reticulum (ER) stress.The immoderate ER stress was verified to aggravate I/R injury in many studies.Grape seed
【机 构】
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Liver Transplantation Center, First Affiliated Hospital of Nanjing Medical University
【出 处】
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中国免疫学会第九届全国免疫学学术大会
论文部分内容阅读
Background: Liver ischemia/reperfusion (I/R) injury induces the occurence of endoplasmic reticulum (ER) stress.The immoderate ER stress was verified to aggravate I/R injury in many studies.Grape seed proanthocyanidin (GSP) was certified as an effective protector in I/R injury.However, the detailed protective mechanisms remain to be ambiguous.Therefore, an endeavor was made to explore the modulation effect of GSP on protection liver I/R injury and alleviating ER stress.
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