论文部分内容阅读
Silver nanoparticles based co-delivery of oseltamivir to inhibit the activity of H1N1 influenza viru
【机 构】
：
Center Laboratory,Guangzhou Women and Children's Medical Center,Guangzhou Medical University
【出 处】
：
第二届纳米医药国际会议(The 2nd International Conference on Nanomedicine
【发表日期】
：
2016年5期
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目的 研究胱天蛋白酶1 对慢性应激所致小鼠抑郁样行为的影响及机制.方法 建立慢性社会挫败性应激小鼠抑郁模型，结合电生理记录和分子生物学技术，观察胱天蛋白酶1 敲除小鼠抑郁样行为以及突触可塑性改变.结果 慢性社会挫败性应激减少小鼠社会接触行为，降低小鼠糖水偏好率，表现出抑郁样行为.抑郁小鼠海马LTP 由(142.7 ± 4.6)％显著降低至(116.6 ± 3.7)％.