Palladium Catalyzed Ketene Coupling with Aryl Iodide

来源 :The 24th International Society of Heterocyclic Chemistry Con | 被引量 : 0次 | 上传用户：bkguo2008

【摘要】

：

An efficient palladium-catalyzed coupling reaction has been developed to generate the aryl ketehes utilizing the ynol ether and aryl iodides.Various synthetically useful intermediates have been produc

【作者】

：

Wenhan Zhang Joseph M.Ready

【机构】

：

Department of Biochemistry,The University of Texas Southwestern Medical Center,5323 Harry Hines Boul

【出处】

：

The 24th International Society of Heterocyclic Chemistry Con

【发表日期】

：

2013年4期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Total Synthesis of Tubingensin A

The first total synthesis of tubingensin A was finished starting from an advanced intermediate of anominine.The synthesis features a CuOTf-promoted 6π-electrocyclization/aromatization sequence to forg

会议

Gram Scale Synthesis of Key Intermediate of Taiwaniaquinoids

A gram scale approach was developed toward the advanced intermediate of taiwaniaquinoids.This intermediate 5a with trans A/B ring junction was concisely assembled by employing a Bi(OTf)3-catalyzed cat

会议

Construction of Spiro-tetrahydroquinolines via Intramolecular Dearomatization of Quinolines: Free of

The stereoselective synthesis of spiro-tetrahydroquinolines has been realized via cacade hydrogenative dearomatization[1] of quinoline and aza-Friedel-Crafts reaction.This methodology features ready a

会议

Highly Regioselective Allylic Substitution Reactions Catalyzed by an Air-stable (π-Allyl)iridium Com

We report an air-stable (π-allyl)iridium complex derived from dinaphthocyclooctatetraene and a phosphoramidite ligand.It was found highly efficient in iridium-catalyzed allylic substitution reactions.

会议

Asymmetric Synthesis of Tetrahydro-β-carbolines via Chiral Phosphoric Acid Catalyzed Transfer Hydrog

An efficient synthesis of enantioenriched tetrahydro-β-carbolines via chiral phosphoric acid catalyzed enantioselective transfer hydrogenation of hydroxylactams has been achieved.This methodology feat

会议

A Chiral Ruthenium-Monophosphine Catalyst for Asymmetric Addition of Arylboronic Acids to Aryl Aldeh

Chiral diarylmethanols are important building blocks for many antihistamine compounds or therapeutic agents such as (R)-orphenadrine, (S)-neobenodine, (S)-carbinoxamine, and bepotastine.catalytic meth

会议

Design of Phosphorus Ligands with Deep Chiral Pockets: Practical Synthesis of Chiral β-Arylamines by

Chiral β-arylamines exist in numerous biologically interesting natural products and therapeutic agents.They also serve as pivotal structural units for many active pharmaceutical ingredients.We have su

会议

Synthesis of γ-Lactam Derivatives via Intramolecular Ene Reaction

Intramolecular ene reactions of the chiral amides 1 and 3 have been established by heating at 160 ℃ in MeCN in sealed vial to furnish the highly functionalized γ-lactams 2 and 4 with good regio-and st

会议

Metal-free Synthesis of Heterocycles from Aryl Triazenes

Several heterocyclic compounds [1-4] have been prepared from aryl triazenes via intramolecular Csp2-Csp2 Friedel-Crafts reactions or direct nucleophilic substitution under metal-free conditions.And re

会议

Direct Synthesis of Fluorinated Heteroarylether Bioisosteres

The direct, one-step synthesis of metabolically stable ether replacements has long been considered a "holy grail" in medicinal chemistry.We developed a modular synthesis of reagents (e.g.sodium difluo

会议

Palladium Catalyzed Ketene Coupling with Aryl Iodide

与本文相关的学术论文