【摘 要】
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Genetic variation in both structural and non-structural genes is a key factor in the capacity of PRRSV to maintain persistence within an animal,and within a production system.However,the exact mechani
【机 构】
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Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine,Kansas State Univ
【出 处】
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2013国际猪繁殖与呼吸综合征学术研讨会
论文部分内容阅读
Genetic variation in both structural and non-structural genes is a key factor in the capacity of PRRSV to maintain persistence within an animal,and within a production system.However,the exact mechanisms of how genetic variation contributes to persistence remain unclear.As part of a study to understand the role of host genetics in disease resistance,we identified pigs that were still viremic at 42 days after PRRSV infection.We took advantage of this subpopulation to identify changes in the genomes of viruses circulating in pigs.The study focused on sequencing nine regions of the genome that show sequence hypervariability.
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