【摘 要】
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Objective:There is currently still no satisfying noninvasive method to diagnosis acute rejection (AR) after kidney transplantation.Meanwhile it is not clear if the AR is related to graft survival.Meth
【机 构】
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Department of Urology,Zhongshan Hospital affiliated to Fudan University,Shanghai,China;Shanghai Key
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Objective:There is currently still no satisfying noninvasive method to diagnosis acute rejection (AR) after kidney transplantation.Meanwhile it is not clear if the AR is related to graft survival.Methods:We investigated a non-invasive method by urinary metabolite profile to detect AR.Gas chromatograph mass spectrometry (GC-MS) in conjunctionwith moderu multivariate statistical techniques was used to analysis 30 urine samples from 15 recipients with different grades of biopsy confirmed AR (Banff 09) and 15 recipients without evidence of rejection.Graft survival was compared between these two groups with five years follow-up.
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