Phosphorylated histone H2AX, also termed γH2AX, mediates the chromatin response to DNA double strand break (DSBs) in mammalian cells and assists DSB repair.
Vigilin, a multi-KH-domain protein, participates in heterochromatin formation.CCCTC-binding factor (CTCF) has been implicated in numerous aspects of chromosome
The Mediator complex orchestrates multiple transcription factors with the Pol Ⅱ apparatus for precise transcriptional control.However, its interplay with t
Glucose metabolic reprogramming is a hallmark of cancer.Cancer cells rapidly adjust their energy source from oxidative phosphorylation to glycolytic metabolism
Objective—Endothelial cells (ECs) form blood vessels through angiogenesis, and participate in maintaining tissue homeostasis by cell fate change through endoth
Pseudouridine is the most abundant post-transcriptional RNA modification.Although pseudouridine is well established in non-coding RNAs, little is known about it
The pentatricopeptide repeat (PPR) proteins are a large family of RNA-binding proteins characterized by tandem repeats of a degenerate 35-amino-acid motif.