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背景:LOX-1是表达于内皮细胞膜上的ox-LDL的主要受体,在动脉粥样硬化(atherosclerosis,AS)发生、发展过程中起重要作用.二氢丹参酮Ⅰ (DHT)是传统中药丹参的脂溶性成分之一.本研究探讨其对LOX-1表达的调控及对AS的改善作用.
二氢丹参酮Ⅰ改善ApoE基因敲除小鼠动脉粥样硬化作用及机制研究
【摘 要】
：
背景:LOX-1是表达于内皮细胞膜上的ox-LDL的主要受体,在动脉粥样硬化(atherosclerosis,AS)发生、发展过程中起重要作用.二氢丹参酮Ⅰ (DHT)是传统中药丹参的脂溶性成分之一.本研究探讨其对LOX-1表达的调控及对AS的改善作用.
【机 构】
：
遵义医学院药理学教研室贵州省基础药理重点实验室,贵州遵义563003 澳门大学,中华医药研究院中药
【出 处】
：
2016年全国抗炎免疫药理学术会议
【发表日期】
：
2016年11期
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