Cardiac-specific Overexpression of CYP2J2 Attenuates Diabetic Cardiomyo pathy in Male Streptozotocin

来源 :2013 Shanghai Symposium on Polyunsaturated Fatty Acids and M | 被引量 : 0次 | 上传用户:wuhanchi
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Cytochrome P450 epoxygenases metabolize arachidonic acid to biologically active cisepoxyeicosatrienoic acids which have potent vasodilatory, anti-inflammatory, anti-apoptotic and antidiabetes properties.
其他文献
PPN基因编码棕榈酰基转移酶,在生成Wnt信号的细胞中负责Wnt蛋白的翻译后棕榈酰化修饰.人们对其在癌症中的表达及作用的研究较少.我们对PPN在胃癌中的异常表达及作用进行了研
会议
  We have shown previously that the calcineurin B subunit (CnB) plays an important role in innate immunity, but little is known of the interactions between Cn
Background Cytochrome P450 2J2 epoxygenase (CYP2J2) converts arachidonic acid into four regioisomeric epoxyeicosatrienoic acids (EETs), which exert multiple pro
Background and objective—Cardiac fibrosis is one of the largest groups of cardiac diseases for which there are very few effective therapies.Our previous study
会议
Introduction:With an increasing incidence of non-alcoholic fatty liver disease (NAFLD) worldwide, intensive research interest has been focused on the molecular
会议
15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is the key enzyme that catalyzes the degradation of prostaglandin E2.15-PGDH is ubiquitously lost in various hum
  The use of extra virgin olive oil in the diet has shown to benefit human health.It is claimed to possess anti-inflammatory activity, reduce cholesterol and
会议
Phagocytosis of apoptotic neutrophils, termed efferocytosis, is essential for the resolution of inflammation as it prevents the exposure of surrounding tissues
The process of resolution of inflammation is actively controlled by endogenous lipid mediators.The phagocytosis of apoptotic neutrophils by macrophages, called
In recent decades, Chinese people have been undergoing rapid nutrition transition, characterized by excessive caloric intakes and increased consumption of anima
会议