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背景：近年来多项研究提示，血循环及尿液中高迁移率族蛋白1 (HMGB1)水平的增加与抗中性粒细胞胞浆抗体相关性小血管炎(AAV)疾病活动性密切相关。抗中性粒细胞胞浆抗体(ANCA)诱导中性粒细胞胞外诱捕网(NET)的形成与AAV的发生发展密切相关。
高迁移率族蛋白1促进抗中性粒细胞胞浆抗体诱导中性粒细胞胞外诱捕网的形成
【摘 要】
：
背景：近年来多项研究提示，血循环及尿液中高迁移率族蛋白1 (HMGB1)水平的增加与抗中性粒细胞胞浆抗体相关性小血管炎(AAV)疾病活动性密切相关。抗中性粒细胞胞浆抗体(ANCA)
【机 构】
：
北京大学第一医院 100034
【出 处】
：
中国免疫学会第十届全国免疫学学术大会
【发表日期】
：
2015年期
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