miRNA在上皮性卵巢癌早/晚期的表达与作用

来源 :中华医学会第十四次全国妇科肿瘤学术会议 | 被引量 : 0次 | 上传用户：sheme2002

【摘要】

：

目的皮性卵巢癌是死亡率最高的妇科恶性肿瘤,其中浆液性乳头状癌(浆乳癌)发病率最高.目前主要的临床挑战是早期诊断和化疗耐药问题.如能在卵巢癌Ⅰ期被发现,病人的治愈率为90％,而卵巢癌Ⅲ-Ⅳ期才被诊断,患者的五年生存率仅为25％.本文拟利用miRNA分子生物学技术,寻找浆乳癌早期与晚期病人的miRNA表达差异,确定与浆乳癌发生发展相关的关键miRNA,探讨与患者预后相关的生物标记物,为浆乳癌早期诊断

【作者】

：

张昕晨于晓棠毕铁丁艳芳赵瑾瑶王畅李天白姜继勇崔世英

【机构】

：

连医科大学研究生院组织胚胎学大连妇产科医院

【出处】

：

中华医学会第十四次全国妇科肿瘤学术会议

【发表日期】

：

2013年7期

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miRNA在上皮性卵巢癌早/晚期的表达与作用

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