【摘 要】
:
Leukemia can be classified into lymphoid and non-lymphoid leukemia.The non-lymphoid leukemia can further be classified into acute and chronic ones.A unique kind of compounds were developed that could
【机 构】
:
Central South University China
论文部分内容阅读
Leukemia can be classified into lymphoid and non-lymphoid leukemia.The non-lymphoid leukemia can further be classified into acute and chronic ones.A unique kind of compounds were developed that could inhibit specifically the bcr/abl fusion gene in CML and one of the compounds was patented by Chinese Patent Office (SIPO).The target compound was newly discovered in the world that could inhibit bcr/abl mRNA expression.
其他文献
The study aims to establish: (1) the optimal planning risk volume (PRV) to the spinal cord (SC) and (2) the impact of the intra-and inter-observer variability in delineation of the parotids on the kil
Radiation therapy is a common treatment option for head-and-neck cancer.During the course of external beam radiotherapy of 6-7 weeks, interfraction anatomic changes (tumor regression, weight loss, etc
Carbon-ion radiotherapy (C-ion RT) offers superior dose distribution in the treatment of tumor volume compared with conventional X-ray radiotherapy.In addition, carbon-ion beam has a higher relative b
Current radiotherapy treatments such as IMRT and VMAT have undergone extensive development and are now reaching to a point of diminishing return.Several technical and clinical advances have called for
The mechanism of radiation-induced delayed brain injuries remains poorly understood, and few treatment options are available.The aim of this study was to investigate whether temporal lobe necrosis can
The interaction between mesenchymal stem cells (MSCs) and dendritic cells (DCs) affects T cell development and function.Further, the chemotactic capacity of MSCs, their interaction with the tumor micr
Research on imaging contrast media over the last decades has led to the discovery of small molecular necrosis-avid compounds (NACs) for the diagnosis of myocardial infarction and therapeutic assessmen
Immunological and biological cancer therapy is now deployed in many settings and is beginning to improve outcomes for cancer patients.There is a pressing need for further innovation and we have develo
Antibody drug conjugate (ADC) is a new class of targeted therapeutics that shows promise in regressing cancers that are resistant to current treatments.In the most simplistic term, an ADC is analogous
We evaluated the safety issues raised by the risk of p53TCR gene transfer-associated on/off-target toxicities in relevant mouse models of adoptive transfer.We provide evidence that an optimized high-a