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  5. A role of microRNA-103/107 in hypoxia-induced pulmonary hypertension of rats

A role of microRNA-103/107 in hypoxia-induced pulmonary hypertension of rats

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：helen527
【摘 要】
：
Background:Hypoxia-induced pulmonary hypertension (PH) is a serious disorder characterized by activation of hypoxia inducible factor-1 (HIF).MicroRNAs play a significant role in modulating vascular re
【作 者】
：
Deng Bi Du Jie Hu Rong Li Yuanjian 
【机 构】
：
Department of Pharmacology,School of Pharmaceutical Science,Central South University,Changsha 410078
【出 处】
：
中国生理学会第24届全国会员代表大会暨生理学学术大会
【发表日期】
：
2014年7期
【关键词】
：
pulmonary hypertension hypoxia microRNA HIF-1β vascular remodeling 
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　　Background:Hypoxia-induced pulmonary hypertension (PH) is a serious disorder characterized by activation of hypoxia inducible factor-1 (HIF).MicroRNAs play a significant role in modulating vascular remodeling in PH.Previous studies have shown that HIF-1β is a target of miR-103/107.
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