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5. Detection of cysteine-and lysine-based 1 protein adductions byreactive metabolites of furan-containi

Detection of cysteine-and lysine-based 1 protein adductions byreactive metabolites of furan-containi

来源 :2015第11届全国药物和化学异物代谢学术会议 | 被引量 : 0次 | 上传用户：zengjinsongduanli

【摘 要】

：

Many furan-containing compounds are known to be toxic and/or carcinogenic.Metabolic activation of toxic furans to cis-enediones (cis-enedials or γ-ketoenals) is generally considered as the initial ste

【作 者】

：

Kai Wang Weiwei Li Jiaming Chen Ying Peng Jiang Zheng 

【机 构】

：

School of Pharmacy, Shenyang Pharmaceutical University,Shenyang 110016, China

【出 处】

：

2015第11届全国药物和化学异物代谢学术会议

【发表日期】

：

2015年9期

【关键词】

：

Furan-containing compounds 2 5-Dimethylfuran Reactive metabolite Protein adducti 

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　　Many furan-containing compounds are known to be toxic and/or carcinogenic.Metabolic activation of toxic furans to cis-enediones (cis-enedials or γ-ketoenals) is generally considered as the initial step towards the processes of their toxicities.

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