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为探讨替硝唑葡萄糖注射液的不同半成品 p H对成品质量的影响 ,采用检测不同半成品 p H时成品的 p H、At、α及 A。结果替硝唑葡萄糖注射液质量稳定的半成品 p H值为 4.0~ 5 .0 ,可减少替硝唑及葡萄糖的分解。在生产过程中 ,半成品 p H应控制 4.0~ 5 .0之间。
To investigate the effect of different semi-finished p H of tinidazole and glucose injection on the quality of the finished product, p H, At, α and A of the finished product were tested when different semi-finished products p H were tested. Results tinidazole glucose injection stable quality semi-finished products p H value of 4.0 to 5.0, can reduce the decomposition of tinidazole and glucose. In the production process, semi-finished p H should be controlled between 4.0 ~ 5.0.