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Liquid crystal(LC)lens had been widely used in many applications,such as 3D display and image capturing.However,most of the LC-lens technologies are currently developed for consumer electronics.For 3D bio-medical image capturing,Integral Imaging(InIm)is one of the potential method,yet has the issues of low image resolution and narrow depth of focus.In this presentation,we had successfully implemented individually tunable LC-lens array for 3D microscope and endoscope applications to yield full resolution and large depth of focus.