【摘 要】
:
Bioorthogonal chemistry, a biocompatible chemical reaction that can occur in the presence of other rich chemical functionalities found in biological systems without interacting or interfering with nat
【机 构】
:
CAS Key Laboratory of Health Informatics, Guangdong Key Laboratory of Nanomedicine,Institute of Biom
【出 处】
:
纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会
论文部分内容阅读
Bioorthogonal chemistry, a biocompatible chemical reaction that can occur in the presence of other rich chemical functionalities found in biological systems without interacting or interfering with native biochemical processes, allows a wide range of bioactive molecules to be specifically labeled in living organisms.
其他文献
Recent research in chemotherapy has prioritized overcoming the multidrug resistance (MDR) of cancer cells.In this work, liposomes that contain doxorubicin (DOX) and ammonium bicarbonate (ABC, a bubble
Anomerism is a common identity encoded by transmembrane glycoproteins and glycolipids,which may influence the biological functions of these glycoconjugates.Here, we investigate comparatively the membr
Recently, the tumorigenesis theory of cancer stem-like cells (CSLCs) has become widely accepted, which states that CSLCs are capable of self-renewal, tumorigenicity and therapeutic resistance.
Berberine (Ber), an isoquinoline derivative alkaloid and active ingredient of Coptis, has been demonstrated to possess anti-diabetic activities.However its low oral bioavailability restricts its clini
The bioactive polymer poly(L-glutamic acid)n-b-poly(D, L-lactic acid)m was synthesized and used to form doxorubicin-loaded hybrid polymeric nanoparticles to treat melanoma.
Chemotherapy is one of the most commonly used systematic treatments for cancer, in which the drug release process is a key factor for drug delivery.[1] In the present study, a real-time monitoring sys
Mifepristone (RU486) ,as an abortifacient, is marketed and used widely by women, and experimentally for psychotic depression and anticancer treatments.Metapristone is the most predominant biological a
Construction and development of novel liver targeted drug delivery systems is a highly desirable strategy to improve drug efficacy and reduce systematic side-effects for liver tumor[1].
It is a potential strategy to increase the selectivity of cell penetrating peptide (CPP) to tumor by the regulation of PEG-Hz-DSPE on the surface of liposomes.In this work, we developed an efficient P
Stimuli-responsive drug delivery systems have been increasingly utilized to promote physiological specificity and on-demand therapeutic efficacy of anticancer drugs.