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5. Generation of orphan GPCR libraries for screening protein/peptideligands

Generation of orphan GPCR libraries for screening protein/peptideligands

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：tiandiren100

【摘 要】

：

G protein-coupled receptors (GPCRs) are the largest group of the cell membrane receptorsplaying critical biological functions.Human genome encodes approximately 400 nonolfactoryGPCRs.So far, the endog

【作 者】

：

Ben-Jun Ji Yu Liu Yu-Qi Guo Lei Zhang Zhan-Yun Guo 

【机 构】

：

Tongji University

【出 处】

：

中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

【发表日期】

：

2014年3期

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G protein-coupled receptors (GPCRs) are the largest group of the cell membrane receptorsplaying critical biological functions.Human genome encodes approximately 400 nonolfactoryGPCRs.So far, the endogenous ligands of approximately 120 GPCRs are remainedunknown and these receptors are termed as orphan GPCRs.

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