Design and synthesis of active peptides based on BRCA1(782-786)and interaction of they with target p

来源 :河南省化学会2018年学术年会 | 被引量 : 0次 | 上传用户：anglelc

【摘要】

：

BRCA1 is known as a crucial tumor suppressor gene,play an important role in cell reproduction,growth,DNA damage repair and the maintenance of genome integrity[1].

【作者】

：

Mengwei Wang Mingxiu Lv Kui Lu Guangbin Liu Zhijie Sun

【机构】

：

College of Chemistry and Molecular Engineering,Zhengzhou University,Zhengzhou 450001,Henan,China

【出处】

：

河南省化学会2018年学术年会

【发表日期】

：

2018年10期

【关键词】

：

BRCA1 RAD51 Solid phase synthesis Interaction

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　BRCA1 is known as a crucial tumor suppressor gene,play an important role in cell reproduction,growth,DNA damage repair and the maintenance of genome integrity[1].

其他文献

离子液体掺杂空穴注入层中电极化界面对OLED性能的影响

会议

可溶液加工型三嗪基超结构分子热延迟荧光材料的合成与表征

热活化延迟荧光(Thermally Activated Delayed Fluorescence,TADF)材料由于单线态(S1)与三线态(T1)之间的能级差较小,使得三线态激子可以通过反向系间窜跃至单线态实现100％激子利用率,在有机发光二极管(OLED)等领域得到广泛应用,被誉为第三代有机发光材料。

会议

热活化延迟荧光(TADF)三嗪基超结构分子(HSM)点击反应溶液加工

TiO2 Nanorings were Prepared with Star-shaped PS-b-PAA as Unimolecular micelle Template

Multi-arm amphiphilic block copolymer(Star-shaped PS-b-PAA)was synthesized by atom transfer radical polymerization(ATRP)with β-cyclodextrin as precursors.

会议

TiO2 nanoringsstar block copolymertemplateprecursor

卤代氨基苯腈共聚合改性氮化碳光催化剂的合成及其光解水制氢

自 2009 年石墨相氮化碳g-C3N4 首次作为光催化剂用于光解水制氢以来,作为可见光驱动的非金属催化剂,g-C3N4 引起了众多研究者的兴趣[1,2].g-C3N4 具有诸多优点,如合适的能带结构、易修饰、廉价等.

会议

石墨相氮化碳卤代氨基苯腈共聚掺杂制氢

Bis(thien-2-yl)-2,1,3-benzothiadiazole-Diketopyrrolopyrrole Based Acceptor-Acceptor Conjugated Polym

Three acceptor-acceptor conjugated copolymers(TBT-DPP,FTBT-DPP and HFTBT-DPP)based on diketopyrrolopyrrole unit and bis(thien-2-yl)-2,1,3-benthothiadiazole unit with different substituent groups as si

会议

Polymer solar cellsAcceptor-acceptor conjugated polymerSynergistic effectBezo

An in situ chemically and physically confined sulfur-polymer composite for lithium sulfur battery wi

Lithium sulfur(Li-S)battery has been considered as one of the most promising energy storage systems for its high theoretical energy density(~2600 Wh kg-1)and the low cost of sulfur.

会议

Lithium sulfur batterysulfur-polymer compositecarbonate-based electrolyte

BRCA1片段肽的设计合成及其与RAD51蛋白的相互作用

肿瘤和癌是细胞失去控制恶性生长的结果，肿瘤或癌的形成，除原癌基因突变为癌基因外，还必需抑癌基因发生突变失活。乳腺癌易感基因Brca 1 是一种重要的抑癌基因[1]，若基因Brca 1 发生突变，则患癌概率明显上升。

会议

BRCA1肽固相合成多肽-蛋白相互作用

Construction of Ce-MOF@COF Hybrid Nanostructure:Non-label Aptasensor for Ultrasensitively Detecting

Porous organic frameworks nanomaterials have been aroused researchers attentions and can be used in various fields.Nevertheless,their applications in the biosensing or biomedical fields are still in t

会议

Cerium-based metal organic frameworkCovalent organic frameworkAptamer sensorD

Copper-Catalyzed Radical Cyclization for Synthesis of 3,3-Difluoro-4-methyl-1-arylpyrrolidin-2-ones

In the past five years,the fluoroalkyl radical addition over a π acceptor has become one of the most straightforward methods to construct C–CF2 bond.Great advances have been achieved in this field.

会议

CopperRadical cyclizationDifluoromethyl group

Cu2O/Ag3PO4-Bi2WO6复合催化剂的制备及可见光催化性能

利用太阳能和半导体材料光催化分解水及降解污染物的技术一直是光催化领域的研究热点[1-2]。本文以水热法制备的巢状Bi2WO6 为基底，通过沉淀法将Ag3PO4 和Cu2O 分别复合在巢状Bi2WO6 上，成功制备不同含量的Cu2O/Ag3PO4-Bi2WO6 复合光催化剂。

会议

Cu2O/Ag3PO4-Bi2WO6光催化氢气烷烃

Design and synthesis of active peptides based on BRCA1(782-786)and interaction of they with target p

与本文相关的学术论文