Seventeen patients with head and neck recurrent carcinoma underwent 125l seed implantation under CT or ultrasound guidance.The actuarial D90 of the 125I seeds implanted was90-160 Gy (median, 126 Gy).Median follow-up was 10 months(range, 3-48 months).The median local control time was 16months; the 1-and 2-year local control rates were 66.5％ and49.9％, respectively.The 1-and 2-year survival rates were51.3％ and 38.5％, respectively (median, 16 months).None of the patients experienced grade 4 toxicity.125l seed implantation was a feasible and effective salvage treatment for patients with recurrent head and neck cancers.