【摘 要】
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Antigenic changes in cancer cells can be recognized by the immune system of patients themselves and presented as immune responses to factors involved in malignant transformation.This is manifested in
【机 构】
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Department of Biological Sciences and NIH-Sponsored Border Biomedical Research Center The University
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Antigenic changes in cancer cells can be recognized by the immune system of patients themselves and presented as immune responses to factors involved in malignant transformation.This is manifested in several ways, one of which is the appearance of circulating autoantibodies.These autoantibodies, which have been called "reporters" from the immune system, can be used as probes in cDNA expression library screening or in proteomics to identify antigens which are involved in the transformation process.
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