Objectives:Pain is an unpleasant sensory and emotional feeling accompanying existing, impending or potential tissue damage.For a decade, it has been promoted as the fifth vital sign.According to the World Health Organization,there are 3 to 5 million patients suffering pain every day globally, of whom 60 to 90% are in severe pain, with 25% of patients dying without pain relief.Pain assessment ought to occur with routine nursing assessments, with changes in a patients condition, on new complaints of pain, with exacerbation and relief of pain, and on changes in activity level.Pain documentation, a critical component of pain management, is the permanent record of pain assessment, intervention, treatment and patient response.Many studies have shown that nurses play the main role in pain management, especially in pain assessment and documentation.With the rapid expansion of electronic medical records and nursing information systems, pain management can be performed accurately and reliably,compared with paper documentation.This study is to develop a pain assessment and record information system for nurses in the Oncology Department, enhancing the quality of pain management, and identifying challenges and facilitators towards the adoption of the pain assessment and record system for nurse leaders.Methods:We describe the framework and function of a pain assessment and record information system, and the implementation of a questionnaire survey to evaluate user s acceptance of the system.