Cartilage oligomeric matrix protein on the phenotype transformation of PASMCs via BMPRⅡ signaling pa

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：sjt111

【摘要】

：

【作者】

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于航倪秀芹朱大岭孔炜

【机构】

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哈尔滨医科大学大庆校区基础医学院大庆 163319 北京大学医学部生理学与病理生理学系北京

【出处】

：

中国生理学会第24届全国会员代表大会暨生理学学术大会

【发表日期】

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2014年7期

【关键词】

：

cartilage oligomeric matrix protein PASMCs phenotype transformation BMPRⅡ

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　　Rationale:Pulmonary arterial hypertension (PAH) is a malignant disease and the pathological mechanism is unclear.Pulmonary arterial remodeling is a major pathological change of PAH and Pulmonary artery smooth muscle (PASMCs) phenotype transformation is the start step in it.Objective:We aimed to indentify the effect of cartilage oligomeric matrix protein (COMP),a normal vascular extracellular matrix,on modulation of PASMCs phenotype.

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Cartilage oligomeric matrix protein on the phenotype transformation of PASMCs via BMPRⅡ signaling pa

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