论文部分内容阅读
Ethnopharmacological relevance: Panax notoginseng(Burk.)F.H.Chen is a widely used traditional Chinese medicine known as Sanqi or Tianqi in China.This plant,which is distributed primarily in the southwest of China,has wide-ranging pharmacological effects and can be used to treat cardiovascular diseases,pain,inflammation and trauma as well as internal and external bleeding due to injury.Aims of the review: This paper provides up-to-date information on investigations of this plant,including its botany,ethnopharmacology,phytochemistry,pharmacology and toxicology.The possible uses and perspectives for future investigation of this plant are also discussed.Materials and Methods: The relevant information on Panax notoginseng(Burk.)F.H.Chen was collected from numerous resources,including classic books about Chinese herbal medicine,and scientific databases,including Pubmed,SciFinder,ACS,Ebsco,Elsevier,Taylor,Wiley and CNKI.Results: More than 200 chemical compounds have been isolated from Panax notoginseng(Burk.)F.H.Chen,including saponins,flavonoids and cyclopeptides.The plant has pharmacological effects on the cardiovascular system,immune system as well as anti-inflammatory,anti-atherosclerotic,haemostatic and anti-tumour activities,etc.Conclusions: Panax notoginseng is a valuable traditional Chinese medical herb with multiple pharmacological effects.This review summarizes the botany,ethnopharmacology,phytochemistry,pharmacology and toxicology of P.notoginseng,and presents the constituents and their corresponding chemical structures found in P.notoginseng comprehensively for the first time.Future research into its phytochemistry of bio-active components should be performed by using bioactivity-guided isolation strategies.Further work on elucidation of the structure-function relationship among saponins,understanding of multi-target network pharmacology of P.notoginseng,as well as developing its new clinical usage and comprehensive utilize will enhance the therapeutic potentials of P.notoginseng.