【摘 要】
:
吖啶衍生物是一类重要的医药和生物中间体,广泛用于合成抗菌药、抗癌药、抗疟疾药[1].其中,一些吖啶衍生物还应用于DNA和RNA的研究工作[2].
【机 构】
:
环境友好化学与应用教育部重点实验室 湘潭大学 化学学院 湘潭 411105
【出 处】
:
中国化学会第九届全国有机化学学术会议
论文部分内容阅读
吖啶衍生物是一类重要的医药和生物中间体,广泛用于合成抗菌药、抗癌药、抗疟疾药[1].其中,一些吖啶衍生物还应用于DNA和RNA的研究工作[2].
其他文献
Chiral carbocyclic nucleosides,in which the D-ribose portion of the nucleoside is replaced by a cyclopentane moiety,have attracted increasing interest.
The pseudo-trisaccharide allosamidin 1(Scheme 1) is a potent inhibitor of all family 18 chitinases,and it is confirmed to have insecticidal and antifungal activities.
The direct methylenation or methylation of C-H bond and heteroatom-H bond,especially methylenation or methylation of Csp3 -H bond and N-H bond,is one of the most important transformation in organic ch
1,3,4-Oxadiazoles represent a significant class of oxygen-containing heterocycles,which are ubiquitous in various biologically active and pharmaceutically important compounds.
The 2-hydroxy-2,3-dihydrofuran moiety widely exist in many natural products and pharmacological molecules(e.g.,Auranfuron A and B,Siphonarienfuranone,Drimanes,Hydroxyfuranone),1,2 which exhibit excell
Herein,we describe a DABCO-catalyzed [2+2] annulation reaction of allenoates with azodicarboxylates which affords 3-alkylidene-1,2-diazetidines in moderate yields and excellent stereo-and regioselecti
Carbon-carbon bond-forming reactions are most important transformation in modern organic chemistry.
氮杂三元环(吖丙啶)的不对称开环反应是制备含氮手性化合物的重要方法,也是具有非常大的挑战性的课题之一.本领域中,前人研究所取得的成功的例子主要局限在对于内消旋吖丙啶(meso-aziridines)去对称化反应的研究上,[1] 而对于2-取代的吖丙啶的不对称反应的成功例子很少,且使用简单手性Lewis 酸催化的体系更未见报道.
Recently,the direct electrophilic α-cyanation of β-keto esters or amides(1)has been accomplished using active hypervalent iodine cyano reagent(C1)which was prepared in our laboratory.
三唑类含能化合物,具有高氮、低碳氢的特点,是一类重要的含能化合物[1-3].4,4′-联-1,2,4-三唑(BTz)是由两个1,2,4-三唑环由4 位的N-N 键连接而成的化合物,可以通过在3,5 位的C进一步引入含能基团拓展BTz 在含能方面的应用.