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CONTENTS BIO-HEAT: Thermal regulation and sensation comfort: Thermoregulation and temperature distribution UnComfort/Pain: Thermal sensation and pain mechanism BIO-MASS: Aerosol deposition in human lungs Airflow structure and particle transportation Total deposition / regional deposition / local deposition BIO-DISTRIBUTION: Air pollutants within body ADME (adsorption, distribution, rnetabolisrn, excretion) process PBPK (Physiologically based pharrnacokinetic) modeling