【摘 要】
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To investigate the effects of acetazolamide on the oxygen uptake of small laboratory animals under hypobaric hypoxia conditions.An automatic,closed-circuit oxygen uptake apparatus is constructed which
【机 构】
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Department of High Altitude Medicine,Institute of Health and Environmental Medicine,Academy of Milit
【出 处】
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中国生理学会第24届全国会员代表大会暨生理学学术大会
论文部分内容阅读
To investigate the effects of acetazolamide on the oxygen uptake of small laboratory animals under hypobaric hypoxia conditions.An automatic,closed-circuit oxygen uptake apparatus is constructed which can be used to measure the oxygen uptake of small animals at any simulated high altitude in a hypobaric chamber.The oxygen uptake of Kunming mice,Hartly guinea pigs and Wistar rats with or without acetazolamide administration at a dose of 45 mg/kg/d for 6 days was sequentially measured at simulated altitudes of 50 m,2,500 m,4,000 m,5,500 m,8,000 m,10,000 m and 11,000 m respectively.
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