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  5. Lipid-induced muscle insulin resistance is mediated by GGPPS via modulation of the RhoA/Rho-kinase s

Lipid-induced muscle insulin resistance is mediated by GGPPS via modulation of the RhoA/Rho-kinase s

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：caoda0512116
【摘 要】
：
Elevated circulating free fatty acid (FFA) levels are major contributors to insulin resistance in the muscle and liver, but the underlying mechanisms require further elucidation.
【作 者】
：
Weiwei Tao Jing Wu Bing-Xian Xie Yuan-Yuan Zhao Ning Shen Shan Jiang Xiu-Xing Wang Na Xu Chen Jiang Shuai Chen Xiang Gao Bin Xue Chao-Jun Li 
【机 构】
：
MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center and the School o
【出 处】
：
中国细胞生物学学会2015年全国学术大会
【发表日期】
：
2015年4期
【关键词】
：
Skeletal muscle GGPPS Protein geranylgeranylation Insulin resistance 
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　　Elevated circulating free fatty acid (FFA) levels are major contributors to insulin resistance in the muscle and liver, but the underlying mechanisms require further elucidation.
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