Bioorthogonal and combinatorial approaches to design functional proteins and peptides

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：rowhwafo

【摘要】

：

【作者】

：

Yoshihiro Ito

【机构】

：

Nano Medical Engineering laboratory,RIKEN,Saitama 351-0198,Japan

【出处】

：

International Conference on Nanoscience & Technology,China 2

【发表日期】

：

2013年3期

【关键词】

：

Bioorthogonal chemistry combinatorial chemistry in vitro selection molecular evo

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Merrifield chemistry enabled us to conveniently synthesize oligonucleotide and peptides.In addition, recombinant DNA technology has allowed us to synthesize new proteins as protein engineering.Recently the protein engineering has been extended into bioorthogonal protein engineering by development of specific chemical or enzymatic modification technology.

其他文献

Preparation of Magnetic Nanoparticles for Molecular Imaging of Tumors

Superparamagnetic iron oxide nanoparticles have received great attention owing to their potential applications as contest agents for magnetic resonance imaging (MRI).Through the thermal decomposition

会议

Application of nanobiotechnology to deliver therapeutic drugs selectively to diseased sites with imp

A number of drugs only give rise to limited clinical response when causing remarkable toxicities due to wide distribution and off-target effects.One possible approach to overcome such limitations is t

会议

NanotechnologydrugSMEDDSRGDtargetingcancercyclodextrinfolic acidestrogen

Nanotoxicity and its chemical mechanisms

More and more nanoscale materials with novel physicochemical properties or new functions have been created and using in different research fields and industrial sectors, meanwhile the scientific and p

会议

The role of self-assembling polypeptides studied by quantitative force spectroscopy

Polypeptides are functional biomolecules that play a key role in life science, where they can act as hormones and signaling molecules.They can self-assemble into a variety of nanostructures, including

会议

PolypeptideAFMSelf-assemblyNanomechanics

Can you speak and write “nano”?

Nanotechnology and nanomedicine are rapidly emerging areas closely related to the emergency of nanoscience [1].Uncovering new materials properties thus developing ways to solve many existing problems

会议

NanotechnologyScientific CommunicationStandardizationNanomedicine trendsComm

Quantum Dots: Synthesis and electrochemiluminescence biosensing

Quantum dots (QDs), also called colloidal semiconductor nanocrystals, have come to the forefront of nanoscience since the turn of this century.QDs possess outstanding optical properties, which make th

会议

Quantum dotsElectrochemiluminescenceBiosensors

Beyond Fluorescence: Small and Bright Theranostic Upconversion Nanoparticles

Functional Lanthanide-doped upconversion luminescent nanoparticles (UCNPs) are promising materials for theranostics due to their unexpected optical and chemical properties.UCNPs absorb low energy near

会议

Upconversion NanoparticleNanomedicineTheranosticsDrug deliveryBiophotonics

Importance of Protein Corona in Nanomedicine

When nanoparticles (NPs) are exposed to the biological environment, their surfaces become covered with proteins and biomolecules [1].Here, we report that this protein coating, or corona, can have sign

会议

protein coronananomedicinetargeting

Biologically-Responsive 19F MRI Agents

Recently there has been intense interest in the development of fluorinated molecules to allow tracking of therapeutic particles and cells in vivo.The motivation for this is the very high selectivity o

会议

MRI19F NMRstar copolymershyperbranched polymers

The creation of Nanodots with combined-dynamic mode “dip-pen” nanolithography technology based on at

Dip-pen nanolithography (DPN), based on atomic force microscope (AFM) system, is an effective technique for nanoscale science and engineering and the potential applications of DPN will be shown in the

会议

Nanodotsdip-pen nanolithography (DPN)depositioninkatomic force microscope (A

Bioorthogonal and combinatorial approaches to design functional proteins and peptides

与本文相关的学术论文