Parkinsons disease(PD)is a progressive neurodegenerative movement disorder that is caused predominantly by the degeneration of the nigrostriatal dopaminergic pathway.
Objective Bisphosphonates(BP)is a category of drugs that are used to treat various bone diseases,such as osteoporosis,Pagets disease,bone malignancy and other skeletal complications involving excessiv
Parkinsons disease(PD)is characterized by degeneration of dopaminergic neurons in the substantia nigra.Besides,the changes of dopaminergic neurons have been reported in enteric nervous system of PD pa
Objective Parkinson disease(PD)is a chronic progressive disease which could involve multiple systems at its early stage while the central nervous system was finally injured at its later stage and mani
We have demonstrated that bradykinin(BK)could increase the permeability of blood-tumor barrier(BTB)via down-regulating the protein expressions of tight junction(TJ)associated protein claudin-5 and occ