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In this contribution we are going to present our modeling activities on tracking microstructure evolution during casting and subsequent homogenization heat treatment of industrial aluminum alloys.Three aluminum alloy systems, i.e., AA3xxx, AA6xxx and AA7xxx have been simulated by our in-house modeling tools and the models predictions have been compared with experimental measurements.It is concluded that the microstructure modeling tools are time and cost effective in optimizing and designing industrial aluminum alloys chemistries and casting and heat treatments parameters.