• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Heterodimerization with full-length NBCn2 enhances surface expression of N-terminally truncated NBCn

Heterodimerization with full-length NBCn2 enhances surface expression of N-terminally truncated NBCn

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：jiangxiuli2010
【摘 要】
：
The electroneutral Na+/HCO3– cotransporter NBCn2,encoded by Slc4a10,a member of the SLC4 family,is highly expressed in the brain and plays a critical role in the production of cerebrospinal fluid and
【作 者】
：
Deng-Ke Wang Ying Liu Jia-Min Li Yi-Min Guo Zhang-Dong Xie Li-Ming Chen 
【机 构】
：
Department of Biophysics and Molecular Physiology,Huazhong University of Science & Technology School
【出 处】
：
中国生理学会第24届全国会员代表大会暨生理学学术大会
【发表日期】
：
2014年7期
【关键词】
：
NBCn2 promoter luciferase assay BiFC pH 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　The electroneutral Na+/HCO3– cotransporter NBCn2,encoded by Slc4a10,a member of the SLC4 family,is highly expressed in the brain and plays a critical role in the production of cerebrospinal fluid and the regulation of neuronal excitability.In a previous study,we have shown that NBCn2 protein is also expressed in the kidney.
其他文献
5-HT modulates the firing activity of subthalamic neurons by multiple receptor mechanisms in 6-OHDA
Objective:The subthalamic nucleus (STN) plays a critical role in movement regulation.It is well known that the firing rate and pattern of the subthalamic neurons is directly related to the manifestati
会议
5-HTsubthalamic nucleusextracellular recordingParkinson
Lateral habenula as a link between dopaminergic and serotonergic systems contributes to depressive s
Degeneration of substantia nigra dopaminergic neurons is an important cause of Parkinsons disease (PD),and its motor consequences have been widely recongized.Recently,mood disorders associated with PD
会议
Later habenula6-hydropamine rat modelDepressive-like behaviorDorsal raphe nuc
Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signali
Objective: Water channel aquaporin-1(AQP1)is expressed at epithelial cell plasma membranes in renal proximal tubules and thin descending limb of Henle.Recently,AQP1 was identified to interact with β-c
会议
蛋白激酶D1(PKD1)通过磷酸化多巴胺D1受体421位点丝氨酸促进可卡因成瘾反应
药物成瘾是危害人类健康的疾病之一,可卡因成瘾是药物成瘾常见的问题,目前尚无有效的治疗手段,我们的研究发现,PKD1 在可卡因成瘾中发挥了正性调控作用。(1) PKD1 广泛分布于大鼠前脑区域,在急性给与大鼠可卡因时能够增加NAc 和纹状体神经元中PKD1 的活性,而抑制PKD1 活性能够降低可卡因引起的运动活性增加；(2)PKD1 能够直接磷酸化多巴胺D1 受体S421 位点,并且由此正性调节多巴
会议
蛋白激酶D1(PKD1)磷酸化可卡因成瘾CPP
XBP1S mediates high glucose induced apoptosis in the cultured renal MCs
Reactive oxygen species (ROS) are crucial in the pathogenesis of diabetic nephropathy (DN).X-box binding protein 1(XBP1),a key mediator of endoplasmic reticulum (ER) stress,has been proved having the
会议
XBP1Sapoptosisendoplasmic reticulum stressmesangial cells
Activation of mammalian target of rapamycin complex 1 (mTORC1) impairs urine concentration in mice
The mammalian target of rapamycin (mTOR) signaling pathway is a master regulator of cell growth.Recently,inhibition of mTOR complex 1 (mTORC1) with rapamycin has also been shown in both clinical and e
会议
mTORC1urine volumerapamycinaquaporin
Intravenously Administered Isogenic iPSs Decrease Kidney Injury Dependent on ROS-Facilitated Engraft
Aims:Induced pluripotent stem cells (iPSs) are believed to have great therapeutic potential.Treatment for acute kidney injury is challenging.Therefore,in the present study,we aimed to demonstrate if i
会议
iPSkidney injuryROS
Cold-induced beige adipogenesis alter lipid metabolism and expression of inflammatory adipokines
Two types of adipose tissue are present in mammals,white and brown (WAT and BAT).While WAT is an energy storage depot,BAT dissipates energy via the mitochondrial uncoupling protein UCP1,defending agai
会议
Beige cellInflammatory adipokinesCold-inducedLipid matabolismAdipogenesis
Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: A novel mechanism of
Background:Albuminuria is not only an important marker of chronic kidney disease,but also a crucial contributor to tubulointerstitial inflammation (TIF).Here we determine whether activation of the Nlr
会议
PGE2 receptor 3 subtype(EP3)regulates adipose metabolism in mice
Preadipocyte and adipocyte are two major cell types that exist in white adipose tissue (WAT).The differentiation of preadipocyte increases the number of mature adipocyte and governs fat content.Trigly
会议
PGE2 receptor 3 subtypeadiposelipogenesislipolysis