论文部分内容阅读
The K1 gene of Kaposis sarcoma-associated herpesvirus (KSHV) is encoded by the first open reading frame (ORF) and lies at the left-end of the KSHV genome.To investigate the role of the K1 gene during the KSHV lifecycle, we constructed a set of recombinant viruses that either wild-type K1, the K1 ORF deleted (KSHV△K1), stop codons within the K1 ORF (KSHV-K15Xstop) or a revertant K1 virus (K1rev).during viral reactivation and replication.