Jilin province is one of the advanced production regions of oriental melon in China, Special local market and technique of production were formed due to the perennial and traditional cultivation, which brought large economic benefit to the farmers who depend on oriental melon planting.With technology innovation in modem agriculture, overcoming technical problem of succession cropping obstacle of oriental melon in production is necessary.In this paper we explore the main problems about the grafting seedling of oriental melon in production, summarize the key technology for oriental melon grafting seedling production and put forward the sustainable development suggestion for the oriental melon grafting seedlings production, which may help stable and healthy oriental melon production.