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Background TARGET Ⅰ randomized controlled trial (RCT) demonstrated that the novel abluminal groove-filled biodegradable polymer sirolimus-eluting stent FIREHAWK (MicroPort Medical,Shanghai,China) was non-inferior to the everolimus-eluting stent with respect to in-stent late loss at 9 months for the treatment of single de novo coronary lesions.The aim of this study was to evaluate the clinical safety and effectiveness of FIREHAWK in a large cohort of patients from the TARGET clinical program.