Solubility Behavior and Thermodynamics of IBU-NIC Cocrystal

来源 :2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 | 被引量 : 0次 | 上传用户：daifeng216216

【摘要】

：

Purpose:The aims of this study were to improve aqueous solubility and dissolution of poorly water-soluble ibuprofen(IBU)by cocrystallization technique and to investigate its solubility behavior and th

【作者】

：

Li Zhang Xiaojie Wang Li Jiu Yuanfeng Wei Yuan Gao Shuai Qian Jiangjun Zhang

【机构】

：

School of Pharmacy,China Pharmaceutical University,Nanjing 211198

【出处】

：

2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年

【发表日期】

：

2016年4期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Preparation and Study of simultaneous delivery of doxorubicin and deoxyschizandrin encapsulated in l

Research showed that crude extracts of schisandra and its active ingredient deoxyschizandrin reversed the effects of multi-drug resistance.

会议

Supramolecular inclusion of nitidine chloride reduced its hepatotoxicity and improved its anticancer

Nitidine chloride(NC),a natural alkaloid isolated from the root of Zanthoxylum nitidum,has demonstrated promising anticancer activity against various types of cancer.However,NC has also shown non-spec

会议

Nitidine chloridecucurbit[7]urilinclusion complexhepatotoxicityanticancer ac

Effect of organic solvents ratio on characteristics of Tanshinone-PLGA microspheres

Background: The organic/water(O/W)emulsion-solvent evaporation method is the most commonly used in fabrication of poly(lactide-co-glycolide)(PLGA)microspheres(MPs),in which dichloromethane(DCM)is usua

会议

TanshinonePLGA microspheresO/W emulsion method

Facile fabrication of TPGS-stabilized liposome-PLGA hybrid nanoparticle via a modified nanoprecipita

会议

Enhancing cellular uptake and anti-tumor efficacy by a non-endocytotic mechanism

A series of biological barriers need to be successfully overcome for effective drug delivery.What standing in the breach of all these hurdles is lysosome.

会议

non-endosomalcytosol localizingHPMA copolymerdoxorubicin

New Design Strategy of Nanomicelles- UA and DOX Dual Drug Nanomicelles Delivery System

Many anticancer drugs because of the poor water solubility has been greatly limited in the clinical application.Nanomicelles are a drug delivery system,the amphiphilic block copolymer micelles refer t

会议

Cyclopamine-loaded polymer nanoparticles reverse the paclitaxel resistance of MCF-7/ADR cells throug

会议

Preparation and Physicochemical Characterization of Coamorphous Repaglinide-Simvastatin

Purpose: The aim of this study was to improve solubility and dissolution of two BCS class II drugs,repaglinide(REP)and simvastatin(ST).

会议

Improved bioavailability and antitumor effect of docetaxel by TPGS modified proniosomes:in vitro and

会议

PLGA nanoparticles for the oral delivery of nuciferine:preparation,physicochemical characterization

OBJECTIVE This study reports a promising approach to enhance the oral delivery of nuciferine(NUC),improve its aqueous solubility and bioavailability,and allow its controlled release as well as inhibit

会议

nuciferinePLGAnanoparticlesbioavailabilitynon-alcoholic fatty liver disease

Solubility Behavior and Thermodynamics of IBU-NIC Cocrystal

与本文相关的学术论文